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Draft Whole-Genome Sequences of Ciprofloxacin-Resistant Derivatives of a Bacillus anthracis ?ANR Strain Lacking pXO1 and pXO2 Plasmids.


ABSTRACT: Mutants of an attenuated Bacillus anthracis (?ANR) strain conferring increasing levels of cipro?oxacin resistance have been described. Here, we report the draft genome sequences of the parent strain (?ANR pXO1-, pXO2-) and its derivatives conferring low (step 1; 0.5??g/ml), medium (step 2; 8 to 16??g/ml), and high (step 3; 32 to 64??g/ml) levels of ciprofloxacin resistance.

SUBMITTER: Biggs TD 

PROVIDER: S-EPMC7380533 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Draft Whole-Genome Sequences of Ciprofloxacin-Resistant Derivatives of a Bacillus anthracis ΔANR Strain Lacking pXO1 and pXO2 Plasmids.

Biggs Tracey D TD   Karavis Mark A MA   Harris Jacquelyn V JV   Hill Jessica M JM   Bernhards Robert C RC   Price Lance B LB   Keim Paul P   Goodwin Bruce G BG   Sozhamannan Shanmuga S  

Microbiology resource announcements 20200409 15


Mutants of an attenuated <i>Bacillus anthracis</i> (ΔANR) strain conferring increasing levels of ciprofloxacin resistance have been described. Here, we report the draft genome sequences of the parent strain (ΔANR pXO1<sup>-</sup>, pXO2<sup>-</sup>) and its derivatives conferring low (step 1; 0.5 μg/ml), medium (step 2; 8 to 16 μg/ml), and high (step 3; 32 to 64 μg/ml) levels of ciprofloxacin resistance. ...[more]

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