Qtl2pleio: Testing pleiotropy vs. separate QTL in multiparental populations.
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ABSTRACT:
SUBMITTER: Boehm F
PROVIDER: S-EPMC7380654 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
qtl2pleio: Testing pleiotropy vs. separate QTL in multiparental populations.
Boehm Frederick F Yandell Brian B Broman Karl W KW
Journal of open source software 20190630 38
Modern quantitative trait locus (QTL) studies in multiparental populations offer opportunities to identify causal genes for thousands of clinical and molecular traits. Traditional analyses examine each trait by itself. However, to fully leverage this vast number of measured traits, the systems genetics community needs statistical tools to analyze multiple traits simultaneously (Jiang & Zeng, 1995; Korol, Ronin, & Kirzhner, 1995). A test of pleiotropy vs. separate QTL is one such tool that will a ...[more]
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