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ABSTRACT:
SUBMITTER: Marinescu M
PROVIDER: S-EPMC7382033 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Marinescu Maria M Cinteză Ludmila Otilia LO Marton George Iuliu GI Chifiriuc Mariana-Carmen MC Popa Marcela M Stănculescu Ioana I Zălaru Christina-Marie CM Stavarache Cristina-Elena CE
BMC chemistry 20200725 1
The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction between benzimidazole, aqueous 30% formaldehyde and an amine, the biological evaluation and DFT studies of the new compounds are reported here. The <sup>1</sup>H-NMR, <sup>13</sup>C-NMR, FTIR spectra and elemental analysis confirm the structures of the new compounds. All synthesized compounds were screened by qualitative and quantitative methods for their in vitro antibacterial activity against 4 bacterial strai ...[more]