Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC7382971 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Zhang Zan Z Huang Hai-Bin HB Jiang Yan-Long YL Liu Jing J Gao Xing X Liu Yang Y Yang Wen-Tao WT Shi Chun-Wei CW Wang Dan D Wang Jian-Zhong JZ Kang Yuan-Huan YH Wang Chun-Feng CF Yang Gui-Lian GL
Parasitology research 20200727 9
Chicken coccidiosis is a protozoan parasitic disease that leads to considerable economic losses in the poultry industry. In this study, we used invasive Lactobacillus plantarum (L.P) expressing the FnBPA protein as a novel bacterial carrier for DNA delivery into epithelial cells to develop a live oral DNA vaccine. A fusion DNA vaccine co-expressing EtMIC2 and chicken IL-18 (chIL-18) was constructed and then delivered to the host by invasive L.P. Its efficacy against Eimeria tenella challenge was ...[more]