Ontology highlight
ABSTRACT:
SUBMITTER: Musacchio L
PROVIDER: S-EPMC7383016 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Musacchio Lucia L Caruso Giuseppe G Pisano Carmela C Cecere Sabrina Chiara SC Di Napoli Marilena M Attademo Laura L Tambaro Rosa R Russo Daniela D Califano Daniela D Palaia Innocenza I Muzii Ludovico L Benedetti Panici Pierluigi P Pignata Sandro S
Cancer management and research 20200722
Advanced, recurrent and metastatic endometrial cancer (EC) has a dismal prognosis due to poor response rates to conventional treatments. In the era of precision medicine, the improved understanding of cancer genetics and molecular biology has led to the development of targeted therapies, such as poly (ADP-ribose) polymerase (PARP) inhibitors. This class of drugs that inhibit PARP enzymes has been investigated in many different types of tumors and its use in the treatment of gynecological maligna ...[more]