Ontology highlight
ABSTRACT:
SUBMITTER: de Laat-Kremers RMW
PROVIDER: S-EPMC7385119 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
de Laat-Kremers Romy M W RMW Yan Qiuting Q Ninivaggi Marisa M de Maat Moniek M de Laat Bas B
Scientific reports 20200727 1
Thrombosis has proven to be extremely difficult to predict. Measuring the generation of thrombin is a very sensitive method to detect changes in the hemostatic system. We developed a method based on the generation of thrombin to further fingerprint hemostasis, which we have named thrombin dynamics. Via this method we are able to exactly measure the prothrombin conversion and thrombin inactivation, and any change in the coagulation cascade will be reflected in these two processes. In the current ...[more]