Ontology highlight
ABSTRACT:
SUBMITTER: Charng J
PROVIDER: S-EPMC7385166 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20200727 1
SIX1/SIX6 polymorphism has been shown to be associated with glaucoma. Studies have also found that, in older adults, retinal nerve fibre layer (RNFL) thickness is significantly thinned with each copy of the risk allele in SIX1/SIX6. However, it is not known whether these genetic variants exert their effects in younger individuals. Comparing a healthy young adult with an older adult cohort (mean age 20 vs 63 years), both of Northern European descent, we found that there was no significant RNFL th ...[more]