Identification of an ATP metabolism-related signature associated with prognosis and immune microenvironment in gliomas.
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ABSTRACT:
SUBMITTER: Huang R
PROVIDER: S-EPMC7385348 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
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Identification of an ATP metabolism-related signature associated with prognosis and immune microenvironment in gliomas.
Huang Ruoyu R Li Guanzhang G Wang Zhiliang Z Hu Huimin H Zeng Fan F Zhang Kenan K Wang Kuanyu K Wu Fan F
Cancer science 20200529 7
As the core element of material and energy metabolism pathways, the biological functions and prognostic significance of ATP metabolism in diffuse gliomas have so far remained unclear. Based on comprehensive analysis of ATP metabolism-related gene expression profiles, we constructed an ATP metabolism-related risk signature to determine the role of ATP metabolism. We found that this ATP metabolism-related gene expression profile could divide patients into 2 robust groups with distinct clinical cha ...[more]
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