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Laboratory testing of invert-cut corrugated metal pipes renewed with polymeric spray applied pipe lining

ABSTRACT: Buried culverts are important components of highway infrastructure. Most large culverts are built decades ago from corrugated metal or reinforced concrete materials and now have reached their design life. A variety of renewal techniques can be utilized to enhance load carrying capacity of the existing deteriorated culverts and extend their design life. Spray applied pipe lining (SAPL) is a trenchless renewal methodology that applies layers of liner on the interior surface of the deteriorated host culvert. The SAPL’s substances generally fall into two categories: cementitious and polymeric materials. Currently, there is no standard method available for structural design of SAPLs that resulting in various methods being applied by SAPL vendors. To provide the essentials for development of a design methodology for SAPLs, the objective of this paper is to examine the structural performance of full scale soil box testing of 60 in. (1.5 m) diameter circular invert deteriorated (invert-cut) corrugated metal pipes (CMPs) renewed with three different thicknesses of polymeric SAPL. The inverts of the CMPs were cut to simulate an invert deteriorated culvert in service condition and maximize the applied static load on the SAPL. The pipe samples were backfilled with loose SP soil and buried under two feet (0.6 m) of soil cover. The performances of SAPL renewed CMPs were compared with a same size invert-cut bare CMP under the same testing configuration. The results indicated that depending on thickness of the polymeric SAPL, application of this method could improve the structural capacity of a fully deteriorated invert CMP culverts up to 80%.

SUBMITTER: Kohankar Kouchesfehani Z

PROVIDER: S-EPMC7386265 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Project description:Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in semipermeable but immunoprotective polymeric membranes. The technology allows for successful transplantation of insulin-producing cells in the absence of immunosuppression. Different approaches of immunoisolation are currently under development. These approaches involve intravascular devices that are connected to the bloodstream and extravascular devices that can be distinguished in micro- and macrocapsules and are usually implanted in the peritoneal cavity or under the skin. The technology has been subject of intense fundamental research in the past decade. It has co-evolved with novel replenishable cell sources for cure of diseases such as Type 1 Diabetes Mellitus that need to be protected for the host immune system. Although the devices have shown significant success in animal models and even in human safety studies most technologies still suffer from undesired tissue responses in the host. Here we review the past and current approaches to modulate and reduce tissue responses against extravascular cell-containing micro- and macrocapsules with a focus on rational choices for polymer (combinations). Choices for polymers but also choices for crosslinking agents that induce more stable and biocompatible capsules are discussed. Combining beneficial properties of molecules in diblock polymers or application of these molecules or other anti-biofouling molecules have been reviewed. Emerging are also the principles of polymer brushes that prevent protein and cell-adhesion. Recently also immunomodulating biomaterials that bind to specific immune receptors have entered the field. Several natural and synthetic polymers and even combinations of these polymers have demonstrated significant improvement in outcomes of encapsulated grafts. Adequate polymeric surface properties have been shown to be essential but how the surface should be composed to avoid host responses remains to be identified. Current insight is that optimal biocompatible devices can be created which raises optimism that immunoisolating devices can be created that allows for long term survival of encapsulated replenishable insulin-producing cell sources for treatment of Type 1 Diabetes Mellitus.

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Laboratory testing of invert-cut corrugated metal pipes renewed with polymeric spray applied pipe lining

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