Deciphering the Enigmatic Function of Pseudomonas Metallothioneins.
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ABSTRACT:
SUBMITTER: Habjanic J
PROVIDER: S-EPMC7387436 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Deciphering the Enigmatic Function of <i>Pseudomonas</i> Metallothioneins.
Habjanič Jelena J Mathew Anugraha A Eberl Leo L Freisinger Eva E
Frontiers in microbiology 20200722
Metallothioneins (MTs) are low molecular weight, Cys-rich proteins that sequester both essential and non-essential metal ions. Despite being highly conserved in the <i>Pseudomonas</i> genus of Gram-negative bacteria, knowledge of their physiological function in this species is scarce. Using the strain <i>P. fluorescens</i> Q2-87 as a model organism, we investigated the role of a conserved MT in zinc homeostasis, cadmium detoxification as well as its implications in stress response. We show that ...[more]
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