LPS-Inducible lncRNA TMC3-AS1 Negatively Regulates the Expression of IL-10.
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ABSTRACT:
SUBMITTER: Ye M
PROVIDER: S-EPMC7387720 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
LPS-Inducible lncRNA TMC3-AS1 Negatively Regulates the Expression of IL-10.
Ye Mengling M Xie Minghong M Zhu Jie J Wang Chen C Zhou Rui R Li Xiaoqing X
Frontiers in immunology 20200722
Long non-coding RNAs are essential regulators of the inflammatory response, especially for transcriptional regulation of inflammatory genes. It has been reported that the expression of transmembrane channel-like 3 (TMC3)-AS1 is increased following lipopolysaccharide stimulation. However, the potential function of TMC3-AS1 in immunity is largely unknown. Herein, we report a specific role for TMC3-AS1 in the regulation of inflammatory gene expression. TMC3-AS1 negatively regulates the expression o ...[more]
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