Efficacy of stem cell therapy for burn wounds: a systematic review and meta-analysis of preclinical studies.

ABSTRACT:

Background

Burns remain a serious public health problem with high morbidity and mortality rates worldwide. Although there are various treatment options available, there is no consensus on the best treatment for severe burns as of yet. Stem cell therapy has a bright prospect in many preclinical studies of burn wounds. The systematic review was performed for these preclinical studies to assess the efficacy and possible mechanisms of stem cells in treating burn wounds.

Methods

Twenty-two studies with 595 animals were identified by searching PubMed, EMBASE, Web of Science, and Cochrane Library databases from inception to 13 May 2020. In addition, a manual search of references of studies was performed to obtain potential studies. No language or time restrictions were enforced. Re

SUBMITTER: Li Y 

PROVIDER: S-EPMC7389817 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature