Ontology highlight
ABSTRACT:
SUBMITTER: Daneshparvar N
PROVIDER: S-EPMC7391215 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Life science alliance 20200727 8
Striated muscle thick filaments are composed of myosin II and several non-myosin proteins. Myosin II's long α-helical coiled-coil tail forms the dense protein backbone of filaments, whereas its N-terminal globular head containing the catalytic and actin-binding activities extends outward from the backbone. Here, we report the structure of thick filaments of the flight muscle of the fruit fly <i>Drosophila melanogaster</i> at 7 Å resolution. Its myosin tails are arranged in curved molecular cryst ...[more]