Ontology highlight
ABSTRACT:
SUBMITTER: Boada-Romero E
PROVIDER: S-EPMC7392086 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Boada-Romero Emilio E Martinez Jennifer J Heckmann Bradlee L BL Green Douglas R DR
Nature reviews. Molecular cell biology 20200406 7
Multiple modes of cell death have been identified, each with a unique function and each induced in a setting-dependent manner. As billions of cells die during mammalian embryogenesis and daily in adult organisms, clearing dead cells and associated cellular debris is important in physiology. In this Review, we present an overview of the phagocytosis of dead and dying cells, a process known as efferocytosis. Efferocytosis is performed by macrophages and to a lesser extent by other 'professional' p ...[more]