Primary B-cell immunodeficiencies.
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ABSTRACT:
SUBMITTER: Smith T
PROVIDER: S-EPMC7395616 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Primary B-cell immunodeficiencies.
Smith Tukisa T Cunningham-Rundles Charlotte C
Human immunology 20181022 6
Primary B-cell immunodeficiencies refer to diseases resulting from impaired antibody production due to either molecular defects intrinsic to B-cells or a failure of interaction between B-cells and T-cells. Patients typically have recurrent infections and can vary with presentation and complications depending upon where the defect has occurred in B-cell development or the degree of functional impairment. In this review, we describe B-cell specific immune defects categorized by presence or absence ...[more]
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