Epidemiological pattern, incidence, and outcomes of COVID-19 in liver transplant patients.

ABSTRACT:

Background & aims

The incidence and outcomes of coronavirus disease 2019 (COVID-19) in immunocompromised patients are a matter of debate.

Methods

We performed a prospective nationwide study including a consecutive cohort of liver transplant patients with COVID-19 recruited during the Spanish outbreak from 28 February to 7 April, 2020. The primary outcome was severe COVID-19, defined as the need for mechanical ventilation, intensive care, and/or death. Age- and gender-standardised incidence and mortality ratios (SIR and SMR) were calculated using data from the Ministry of Health and the Spanish liver transplant registry. Independent predictors of severe COVID-19 among hospitalised patients were analysed using multivariate Cox regression.

Results

A total of 111 liver tr

SUBMITTER: Colmenero J 

PROVIDER: S-EPMC7395653 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature