Ontology highlight
ABSTRACT:
SUBMITTER: Perchetti GA
PROVIDER: S-EPMC7396208 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Perchetti Garrett A GA Sullivan Ka-Wing KW Pepper Greg G Huang Meei-Li ML Breit Nathan N Mathias Patrick P Jerome Keith R KR Greninger Alexander L AL
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20200802
<h4>Background</h4>SARS-CoV-2 testing demand has outpaced its supply. Pooling samples for lower risk populations has the potential to accommodate increased demand for SARS-CoV-2 molecular testing.<h4>Objective</h4>To evaluate the sensitivity, specificity, and reproducibility of 4-way pooling of SARS-CoV-2 specimens for high-throughput RT-PCR.<h4>Study design</h4>Individual samples were pooled 1:4 through automated liquid handling, extracted, and assayed by our emergency use authorized CDC-based ...[more]