Ontology highlight
ABSTRACT:
SUBMITTER: Mitri C
PROVIDER: S-EPMC7396676 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mitri Christie C Xu Zhengzhong Z Bardin Pauline P Corvol Harriet H Touqui Lhousseine L Tabary Olivier O
Frontiers in pharmacology 20200723
Cystic fibrosis (CF) is the most common genetic disorder among Caucasians, estimated to affect more than 70,000 people in the world. Severe and persistent bronchial inflammation and chronic bacterial infection, along with airway mucus obstruction, are hallmarks of CF lung disease and participate in its progression. Anti-inflammatory therapies are, therefore, of particular interest for CF lung disease. Furthermore, a better understanding of the molecular mechanisms involved in airway infection an ...[more]