<i>Prochlorococcus</i> phage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases.

ABSTRACT: Marine cyanobacteria are infected by phages whose genomes encode ferredoxin (Fd) electron carriers. These Fds are thought to redirect the energy harvested from light to phage-encoded oxidoreductases that enhance viral fitness, but it is unclear how the biophysical properties and partner specificities of phage Fds relate to those of photosynthetic organisms. Here, results of a bioinformatics analysis using a sequence similarity network revealed that phage Fds are most closely related to cyanobacterial Fds that transfer electrons from photosystems to oxidoreductases involved in nutrient assimilation. Structural analysis of myovirus P-SSM2 Fd (pssm2-Fd), which infects the cyanobacterium Prochlorococcus marinus, revealed high levels of similarity to cyanobacterial Fds (root mean square

SUBMITTER: Campbell IJ 

PROVIDER: S-EPMC7397100 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature