Characteristics and reference ranges of CD4⁺T cell subpopulations among healthy adult Han Chinese in Shanxi Province, North China.

ABSTRACT:

Background

Immunophenotyping of blood lymphocytes is an essential tool to evaluate the immune function of patients with immunodeficiency or autoimmunity. Predominately identified CD4⁺T cell subsets, Th1, Th2, Th17, as well as regulatory T (Treg) cells, play crucial roles in several immunological and pathological conditions. Considering the variations in cell counts among populations and ethnicities, specific CD4⁺T cell subset reference values need to be locally established to enable meaningful comparisons and accurate data interpretation in clinical and research settings. Therefore, the aim of this study was to establish distributions and reference ranges for blood CD4⁺T cell subpopulations in age- and sex-balanced healthy adults of a Han Chinese po

SUBMITTER: Niu HQ 

PROVIDER: S-EPMC7397677 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature