Ontology highlight
ABSTRACT:
SUBMITTER: Gallucci G
PROVIDER: S-EPMC7399440 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Gallucci Giuseppina G Tartarone Alfredo A Lerose Rosa R Lalinga Anna Vittoria AV Capobianco Alba Maria AM
Journal of thoracic disease 20200701 7
Smoking increases mortality from all causes and has a crucial role in atherosclerotic cardiovascular disease (ASCVD). Active smoking and secondhand smoke exposure determine more than 30% of coronary heart disease (CHD) mortality. The exact mechanisms of cardiovascular damages are not well known, but the detrimental effect of smoking on endothelial function has long been recognized. Smoking elicits oxidative processes, negatively affects platelet function, fibrinolysis, inflammation and vasomotor ...[more]