Ontology highlight
ABSTRACT:
SUBMITTER: Dumonteil E
PROVIDER: S-EPMC7400351 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Dumonteil Eric E Herrera Claudia C
Pathogens (Basel, Switzerland) 20200717 7
The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are based on the Spike glycoprotein (S) or the Nucleocapsid (N) viral protein. Conservation of these antigens among viral strains is critical to ensure optimum diagnostic test performance and broad protective efficacy, respectively. We assessed N and S antigen diversity from 17,853 SARS-CoV-2 genome sequences and evaluated selection pressure. Up to 6-7 in ...[more]