Ontology highlight
ABSTRACT:
SUBMITTER: Monsalves-Alvarez M
PROVIDER: S-EPMC7400376 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Monsalves-Alvarez Matías M Morales Pablo Esteban PE Castro-Sepulveda Mauricio M Sepulveda Carlos C Rodriguez Juan Manuel JM Chiong Mario M Eisner Verónica V Lavandero Sergio S Troncoso Rodrigo R
Nutrients 20200629 7
β-hydroxybutyrate is the main ketone body generated by the liver under starvation. Under these conditions, it can sustain ATP levels by its oxidation in mitochondria. As mitochondria can modify its shape and function under different nutritional challenges, we study the chronic effects of β-hydroxybutyrate supplementation on mitochondrial morphology and function, and its relation to exercise capacity. Male C57BL/6 mice were supplemented with β-hydroxybutyrate mineral salt (3.2%) or control (CT, N ...[more]