Ontology highlight
ABSTRACT:
SUBMITTER: Chen M
PROVIDER: S-EPMC7403400 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chen Menglong M Wang Liang L Li Yaqin Y Chen Yongjun Y Zhang Huili H Zhu Yuling Y He Ruojie R Li Huan H Lin Jinfu J Zhang Yu Y Zhang Cheng C
Frontiers in neurology 20200729
<b>Background:</b> Duchenne muscular dystrophy (DMD) is a fatal, X-linked recessive muscle disorder characterized by heterogeneous progression and severity. We aimed to study the effects of single nucleotide polymorphisms (SNPs) in <i>SPP1</i> and <i>LTBP4</i> on DMD progression in Chinese patients. <b>Methods:</b> We genotyped <i>LTBP4</i> haplotypes and the <i>SPP1</i> promoter SNPs rs28357094, rs11730582, and rs17524488 in 326 patients registered in the neuromuscular database of The First Aff ...[more]