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Cardiac angiosarcoma: A diagnostic and therapeutic challenge.

ABSTRACT: Cardiac angiosarcomas are a rare group of soft tissue sarcomas, characterized by aggressive local growth and early spread. Because this is an uncommon disease, there is currently no standard treatment approach. When localized, surgery appears to lead to the best outcomes, but this can be technically challenging and not always feasible. Upfront chemoradiotherapy provides an alternative that may shrink the tumor to enable definitive surgical resection. We report a case of primary cardiac angiosarcoma with a complete metabolic and pathological response after upfront chemoradiotherapy with paclitaxel, who then underwent surgery, as a potential treatment option for patients with this rare condition. .

SUBMITTER: Krishnan T

PROVIDER: S-EPMC7403564 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Cardiac angiosarcoma: A diagnostic and therapeutic challenge.

Krishnan Tharani T Pettersson Gosta G Mukherjee Rahul R Singhal Nimit N

Journal of cardiology cases 20200514 2

Cardiac angiosarcomas are a rare group of soft tissue sarcomas, characterized by aggressive local growth and early spread. Because this is an uncommon disease, there is currently no standard treatment approach. When localized, surgery appears to lead to the best outcomes, but this can be technically challenging and not always feasible. Upfront chemoradiotherapy provides an alternative that may shrink the tumor to enable definitive surgical resection. We report a case of primary cardiac angiosarc ...[more]

PMID: 32774528

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