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Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components.


ABSTRACT: Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical space and chemical diversity of these compounds. The results demonstrated that both honey bee propolis and stingless bee propolis are valuable sources for pharmaceutical and nutraceutical development.

SUBMITTER: Tran TD 

PROVIDER: S-EPMC7404124 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components.

Tran Trong D TD   Ogbourne Steven M SM   Brooks Peter R PR   Sánchez-Cruz Norberto N   Medina-Franco José L JL   Quinn Ronald J RJ  

International journal of molecular sciences 20200715 14


Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical  ...[more]

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