Ontology highlight
ABSTRACT:
SUBMITTER: Taydakov IV
PROVIDER: S-EPMC7404147 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20200728
Diethyl 2-(perfluorophenyl)malonate was synthesized in 47% isolated yield by the reaction of sodium diethyl malonate and hexafluorobenzene. The resulting compound was considered as a starting material for synthesizing 2-(perfluorophenyl)malonic acid by hydrolysis. It was found that the desired 2-(perfluorophenyl)malonic acid could not be obtained from this ester by hydrolysis, neither under basic nor under acidic conditions. Nevertheless, hydrolysis of the ester with a mixture of HBr and AcOH ga ...[more]