Ontology highlight
ABSTRACT:
SUBMITTER: Neri-Castro E
PROVIDER: S-EPMC7405010 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Neri-Castro Edgar E Bénard-Valle Melisa M Paniagua Dayanira D V Boyer Leslie L D Possani Lourival L López-Casillas Fernando F Olvera Alejandro A Romero Camilo C Zamudio Fernando F Alagón Alejandro A
Toxins 20200717 7
The most abundant protein families in viper venoms are Snake Venom Metalloproteases (SVMPs), Snake Venom Serine Proteases (SVSPs) and Phospholipases (PLA<sub>2</sub>s). These are primarily responsible for the pathophysiology caused by the bite of pit-vipers; however, there are few studies that analyze the pharmacokinetics (PK) of whole venom (WV) and its protein families. We studied the pathophysiology, PK profile and differential absorption of representative toxins from venom of Neotropical Rat ...[more]