Ontology highlight
ABSTRACT:
SUBMITTER: Giorgianni F
PROVIDER: S-EPMC7407600 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Giorgianni Francesco F Ernst Pierre P Dell'Aniello Sophie S Suissa Samy S Renoux Christel C
American journal of epidemiology 20200801 8
A recent study found a decreased risk of Parkinson disease (PD) associated with the β2 adrenergic agonist (β2-agonist) salbutamol. However, other mechanisms might explain this apparent association. Using the UK Clinical Practice Research Datalink, we formed a cohort of 2,430,884 patients aged 50 years or older between 1995 and 2016. During follow-up, 8,604 cases of PD were identified and matched to 86,040 controls on sex, age, date of cohort entry, and duration of follow-up, after applying a 1-y ...[more]