Ontology highlight
ABSTRACT:
SUBMITTER: Awada H
PROVIDER: S-EPMC7407619 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Awada Hassan H Voso Maria Teresa MT Guglielmelli Paola P Gurnari Carmelo C
Cancers 20200630 7
Over the past decade, new insights have emerged on the pathophysiology of essential thrombocythemia (ET), its clinical management, and associated thrombohemostatic disturbances. Here, we review the latest diagnostic and risk stratification modalities of ET and its therapeutics. Moreover, we discuss the clinical evidence-based benefits, deriving from major clinical trials, of using cytoreductive therapy and antiplatelet agents to lower the risk of fatal vascular events. Also, we focus on the cond ...[more]