Ontology highlight
ABSTRACT:
SUBMITTER: Terraza-Aguirre C
PROVIDER: S-EPMC7408034 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Terraza-Aguirre Claudia C Campos-Mora Mauricio M Elizondo-Vega Roberto R Contreras-López Rafael A RA Luz-Crawford Patricia P Jorgensen Christian C Djouad Farida F
Cells 20200710 7
Mesenchymal stem cells (MSCs) exhibit potent immunoregulatory abilities by interacting with cells of the adaptive and innate immune system. In vitro, MSCs inhibit the differentiation of T cells into T helper 17 (Th17) cells and repress their proliferation. In vivo, the administration of MSCs to treat various experimental inflammatory and autoimmune diseases, such as rheumatoid arthritis, type 1 diabetes, multiple sclerosis, systemic lupus erythematosus, and bowel disease showed promising therape ...[more]