Ontology highlight
ABSTRACT:
SUBMITTER: Dajnowicz S
PROVIDER: S-EPMC7408236 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Dajnowicz Steven S Cheng Yongqiang Y Daemen Luke L LL Weiss Kevin L KL Gerlits Oksana O Mueser Timothy C TC Kovalevsky Andrey A
ACS omega 20200723 30
Protein dynamics on various time scales from femtoseconds to milliseconds impacts biological function by driving proteins to conformations conducive to ligand binding and creating functional states in enzyme catalysis. Neutron vibrational spectroscopy carried out by measuring inelastic neutron scattering from protein molecules in combination with molecular simulations has the unique ability of detecting and visualizing changes in the picosecond protein vibrational dynamics due to ligand binding. ...[more]