Ontology highlight
ABSTRACT:
SUBMITTER: Chien YC
PROVIDER: S-EPMC7408254 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Chien Yi-Chung YC Chen Jia-Ni JN Chen Ya-Huey YH Chou Ruey-Hwang RH Lee Han-Chung HC Yu Yung-Luen YL
Cancers 20200703 7
Glioblastoma (GBM) is the most common primary brain tumor in adults. Tumor invasion is the major reason for treatment failure and poor prognosis in GBM. Inhibiting migration and invasion has become an important therapeutic strategy for GBM treatment. Enhancer of zeste homolog 2 (EZH2) and C-X-C motif chemokine receptor 4 (CXCR4) have been determined to have important roles in the occurrence and development of tumors, but the specific relationship between EZH2 and CXCR4 expression in GBM is less ...[more]