Ontology highlight
ABSTRACT:
SUBMITTER: Cedzynski M
PROVIDER: S-EPMC7408476 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Cancers 20200704 7
The complement system is activated cascadically via three distinct major routes: classical pathway (CP), alternative pathway (AP) or lectin pathway (LP). The unique factors associated with the latter are collectins (mannose-binding lectin, collectin-10, collectin-11), ficolins (ficolin-1, ficolin-2, ficolin-3) and proteins of the mannose-binding lectin-associated serine protease (MASP) family (MASP-1, MASP-2, MASP-3, MAp19, MAp44). Collectins and ficolins are both pattern-recognising molecules ( ...[more]