External Validation of the International IgA Nephropathy Prediction Tool.

ABSTRACT:

Background and objectives

The International IgA Nephropathy Network recently developed and externally validated two models to predict the risk of progression of IgA nephropathy: full models without and with race. This study sought to externally validate the International IgA Nephropathy Prediction Tool in a large, independent, and contemporary cohort in China.

Design, setting, participants, & measurements

We included 1373 patients with biopsy-confirmed primary IgA nephropathy from The First Affiliated Hospital of Zhengzhou University from January 2012 to May 2018 and calculated predicted risks for each patient. The outcomes of interest were a 50% decline in eGFR or kidney failure. We assessed the performance of both models using discrimination (concordance statistics and Kap

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7409753 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature