Ontology highlight
ABSTRACT:
SUBMITTER: Colas P
PROVIDER: S-EPMC7410148 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Orphanet journal of rare diseases 20200806 1
Extensive studies in the past 30 years have established that cyclin-dependent kinases (CDKs) exert many diverse, important functions in a number of molecular and cellular processes that are at play during development. Not surprisingly, mutations affecting CDKs or their activating cyclin subunits have been involved in a variety of rare human developmental disorders. These recent findings are reviewed herein, giving a particular attention to the discovered mutations and their demonstrated or hypot ...[more]