Metabolic radiogenomics in lung cancer: associations between FDG PET image features and oncogenic signaling pathway alterations.
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ABSTRACT:
SUBMITTER: Kim G
PROVIDER: S-EPMC7411040 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
Metabolic radiogenomics in lung cancer: associations between FDG PET image features and oncogenic signaling pathway alterations.
Kim Gahyun G Kim Jinho J Cha Hongui H Park Woong-Yang WY Ahn Jin Seok JS Ahn Myung-Ju MJ Park Keunchil K Park Yong-Jin YJ Choi Joon Young JY Lee Kyung-Han KH Lee Se-Hoon SH Moon Seung Hwan SH
Scientific reports 20200806 1
This study investigated the associations between image features extracted from tumor <sup>18</sup>F-fluorodeoxyglucose (FDG) uptake and genetic alterations in patients with lung cancer. A total of 137 patients (age, 62.7 ± 10.2 years) who underwent FDG positron emission tomography/computed tomography (PET/CT) and targeted deep sequencing analysis for a tumor lesion, comprising 61 adenocarcinoma (ADC), 31 squamous cell carcinoma (SQCC), and 45 small cell lung cancer (SCLC) patients, were enrolled ...[more]
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