Neuroinflammation PET Imaging: Current Opinion and Future Directions.
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ABSTRACT:
SUBMITTER: Jain P
PROVIDER: S-EPMC7413228 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
Neuroinflammation PET Imaging: Current Opinion and Future Directions.
Jain Poorva P Chaney Aisling M AM Carlson Mackenzie L ML Jackson Isaac M IM Rao Anoushka A James Michelle L ML
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20200703 8
Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however, its exact role in vivo is yet to be fully understood. PET imaging enables investigation, quantification, and tracking of different neuroinflammation biomarkers in living subjects longitudinally. One such biomarker that has been imaged extensively using PET is translocator protein 18 kDa (TSPO). Although imaging TSPO has yielded valuable clinical data linking neuroinflammation to various neurodegenerative dis ...[more]
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