A study on the response of FRET based DNA aptasensors in intracellular environment.
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ABSTRACT:
SUBMITTER: Ghosh S
PROVIDER: S-EPMC7413375 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
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A study on the response of FRET based DNA aptasensors in intracellular environment.
Ghosh Shreya S Chen Yinghua Y Sebastian Jesvin J George Anne A Dutta Mitra M Stroscio Michael A MA
Scientific reports 20200806 1
This paper presents a study of the response of FRET based DNA aptasensors in the intracellular environment. Herein, we extend previous studies of aptasensors functioning in the extracellular environment to detection of antigens in the intracellular environment. An essential step in this research is the use of a novel means of achieving the endocytosis of aptasensors. Specifically, it is demonstrated that functioning aptasensors are successfully endocytosed by functionalizing the aptasensors with ...[more]
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