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Energy-dense, low-volume paediatric oral nutritional supplements improve total nutrient intake and increase growth in paediatric patients requiring nutritional support: results of a randomised controlled pilot trial.


ABSTRACT: Children with or at risk of faltering growth require nutritional support and are often prescribed oral nutritional supplements (ONS). This randomised controlled trial investigated the effects of energy-dense paediatric ONS (2.4 kcal/ml, 125 ml: cONS) versus 1.5 kcal/ml, 200 ml ONS (sONS) in community-based paediatric patients requiring oral nutritional support. Fifty-one patients (mean age 5.8 years (SD 3)) with faltering growth and/or requiring ONS to meet their nutritional requirements were randomised to cONS (n?=?27) or sONS (n?=?24) for 28 days. Nutrient intake, growth, ONS compliance and acceptability, appetite and gastro-intestinal tolerance were assessed. Use of the cONS resulted in significantly greater mean total daily energy (+?531 kcal/day), protein (+?10.1 g/day) and key micronutrient intakes compared with the sONS group at day 28 and over time, due to high ONS compliance (81% of patients ??75%), maintained intake from diet alone and improved appetite in the cONS group, compared with the sONS group. Although growth increased in both intervention groups, results were significant in the cONS group (weight (p?=?0.007), height (p?

SUBMITTER: Hubbard GP 

PROVIDER: S-EPMC7413916 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Energy-dense, low-volume paediatric oral nutritional supplements improve total nutrient intake and increase growth in paediatric patients requiring nutritional support: results of a randomised controlled pilot trial.

Hubbard Gary P GP   Fry Catherine C   Sorensen Katy K   Casewell Catherine C   Collins Lydia L   Cunjamalay Annaruby A   Simpson Michelle M   Wall Amanda A   Van Wyk Elmarie E   Ward Matthew M   Hallowes Sophie S   Duggan Hannah H   Robison Jennifer J   Gane Helen H   Pope Lucy L   Clark Jennifer J   Stratton Rebecca J RJ  

European journal of pediatrics 20200313 9


Children with or at risk of faltering growth require nutritional support and are often prescribed oral nutritional supplements (ONS). This randomised controlled trial investigated the effects of energy-dense paediatric ONS (2.4 kcal/ml, 125 ml: cONS) versus 1.5 kcal/ml, 200 ml ONS (sONS) in community-based paediatric patients requiring oral nutritional support. Fifty-one patients (mean age 5.8 years (SD 3)) with faltering growth and/or requiring ONS to meet their nutritional requirements were ra  ...[more]

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