The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity.
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ABSTRACT:
SUBMITTER: Wei BL
PROVIDER: S-EPMC7414557 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity.
Wei Bi-Liu BL Yin Rui-Xing RX Liu Chun-Xiao CX Deng Guo-Xiong GX Guan Yao-Zong YZ Zheng Peng-Fei PF
Molecular medicine (Cambridge, Mass.) 20200808 1
<h4>Background</h4>Little is known about the correlation between the melanocortin 4 receptor gene (MC4R) single nucleotide polymorphisms (SNPs) and the risk of obesity. This research sought to test the MC4R rs17782313, rs476828 and rs12970134 SNPs, their haplotypes and gene-environment interactions on the risk of obesity in the Maonan ethnic group, an isolated minority in China.<h4>Methods</h4>A case-control study comprised of 1836 participants (obesity group, 858; and control group, 978) was co ...[more]
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