Resolution-dependent influences of compressed sensing in quantitative T2 mapping of articular cartilage.

ABSTRACT: This study evaluates the resolution-dependent influences of compressed sensing (CS) in MRI quantification of T2 mapping in articular cartilage with osteoarthritis (OA). T2-weighed 2D experiments of healthy and OA cartilage were fully sampled in k-space with five echo times at both 17.6 μm and 195.3 μm in-plane resolutions; termed as microscopic MRI (μMRI) and macroscopic MRI (mMRI) respectively. These fully sampled k-space data were under-sampled at various 2D CS accelerating factors (AF = 4-32). The under-sampled data were reconstructed individually into 2D images using nonlinear reconstruction, which were used to calculate the T2 maps. The bulk and zonal variations of T2 values in cartilage were evaluated at different AFs. The study finds that the T2 images at AFs up to 8 preserved major

SUBMITTER: Wang N 

PROVIDER: S-EPMC7415577 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature