Ontology highlight
ABSTRACT:
SUBMITTER: Ur Rahman M
PROVIDER: S-EPMC7416170 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Ur Rahman Mujeeb M Wang Ping P Wang Na N Chen Yaodong Y
Bosnian journal of basic medical sciences 20200803 3
Nowadays, the emergence of multidrug-resistant bacterial strains initiates the urgent need for the elucidation of the new drug targets for the discovery of antimicrobial drugs. Filamenting temperature-sensitive mutant Z (FtsZ), a eukaryotic tubulin homolog, is a GTP-dependent prokaryotic cytoskeletal protein and is conserved among most bacterial strains. In vitro studies revealed that FtsZ self-assembles into dynamic protofilaments or bundles and forms a dynamic Z-ring at the center of the cell ...[more]