Approaches and Challenges in SARS-CoV-2 Vaccine Development.
Ontology highlight
ABSTRACT:
SUBMITTER: Dagotto G
PROVIDER: S-EPMC7416703 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Approaches and Challenges in SARS-CoV-2 Vaccine Development.
Dagotto Gabriel G Yu Jingyou J Barouch Dan H DH
Cell host & microbe 20200810 3
The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history. Multiple SARS-CoV-2 vaccine candidates have been evaluated in preclinical models and are currently in clinical trials. In this Perspective, we discuss three topics that are critical for SARS-CoV-2 vaccine development: antigen selection and engineering, preclinical challenge studies in no ...[more]
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