Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC7417398 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wu Henggang H Li Xu X Zhang Tiehui T Zhang Guojun G Chen Jingnan J Chen Li L He Min M Hao Bilie B Wang Cheng C
Neuromolecular medicine 20200221 3
Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance. Previous studies showed that Allicin could inhibit multiple cancer cells including glioblastoma, but the function of Allicin in glioblastoma is still unclear. Our work aimed to investigate the underlying molecular mechanism. The results showed that miR-486-3p levels were greatly increased in glioblastoma during Allicin treatment. Overexpression of miR-486-3p increased chemosensitivi ...[more]