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Mitochondrial DNA control region variation in a population sample from Thailand.


ABSTRACT: Mitochondrial DNA (mtDNA) control region sequences from hair samples of 213 individuals from Thailand were analyzed using Sanger sequencing. A total of 170 different haplotypes were identified, of which 146 occurred only once (unique haplotypes). The dataset showed a random match probability of 0.87% and a haplotype diversity of 0.9960. The samples were assigned to 85 different haplogroups with B5a, F1a1a, and M being the most frequent ones. Pairwise FST-values between this and other Southeast and East Asian populations revealed significant but relatively low differences, indicating a close relation. Heteroplasmic positions were observed in 12.2% of hair samples confirming the frequent appearance of heteroplasmic positions in hairs. This dataset will complement existing data as an mtDNA reference for forensic investigations.

SUBMITTER: Sauer DC 

PROVIDER: S-EPMC7417404 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Mitochondrial DNA control region variation in a population sample from Thailand.

Sauer Dirk Christopher DC   Naue Jana J   Immel Uta-Dorothee UD   Lutz-Bonengel Sabine S  

International journal of legal medicine 20200501 5


Mitochondrial DNA (mtDNA) control region sequences from hair samples of 213 individuals from Thailand were analyzed using Sanger sequencing. A total of 170 different haplotypes were identified, of which 146 occurred only once (unique haplotypes). The dataset showed a random match probability of 0.87% and a haplotype diversity of 0.9960. The samples were assigned to 85 different haplogroups with B5a, F1a1a, and M being the most frequent ones. Pairwise F<sub>ST</sub>-values between this and other  ...[more]

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