Ontology highlight
ABSTRACT:
SUBMITTER: Rachdi L
PROVIDER: S-EPMC7417582 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Rachdi Latif L Maugein Alicia A Pechberty Severine S Armanet Mathieu M Hamroune Juliette J Ravassard Philippe P Marullo Stefano S Albagli Olivier O Scharfmann Raphael R
Scientific reports 20200810 1
G protein-coupled receptors are seven transmembrane signaling molecules that are involved in a wide variety of physiological processes. They constitute a large protein family of receptors with almost 300 members detected in human pancreatic islet preparations. However, the functional role of these receptors in pancreatic islets is unknown in most cases. We generated a new stable human beta cell line from neonatal pancreas. This cell line, named ECN90 expresses both subunits (GABBR1 and GABBR2) o ...[more]