Ontology highlight
ABSTRACT:
SUBMITTER: Adashek JJ
PROVIDER: S-EPMC7418523 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Adashek Jacob J JJ Arroyo-Martinez Yadis Y Menta Arjun K AK Kurzrock Razelle R Kato Shumei S
Frontiers in oncology 20200804
Gastric cancer remains third leading cause of global cancer mortality and is the fifth most common type of cancer in the United States. A select number of gastric cancers harbor alterations in <i>EGFR</i> and/or have amplification/overexpression in the HER2; 2-35 and 9-38%, respectively. The advent of next-generation sequencing of tissue and circulating tumor DNA has allowed for the massive expansion of targeted therapeutics to be employed in many settings. There have been a handful of trials us ...[more]