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Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma.


ABSTRACT: Enhanced radiosensitivity is an uncommon phenomenon attributable to deficient DNA repair after radiotherapy which can be assessed with the ?-H2AX assay. Reports of radiosensitivity after stereotactic radiosurgery (SRS) are uncommon. We describe a case where the clinical, radiological and laboratory findings suggest enhanced radiosensitivity after SRS for an acoustic neuroma.

SUBMITTER: Adams G 

PROVIDER: S-EPMC7418889 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma.

Adams Gerard G   Martin Olga A OA   Roos Daniel E DE   Lobachevsky Pavel N PN   Potter Andrew E AE   Zacest Andrew C AC   Bezak Eva E   Bonner William M WM   Martin Roger F RF   Leong Trevor T  

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120503 3


Enhanced radiosensitivity is an uncommon phenomenon attributable to deficient DNA repair after radiotherapy which can be assessed with the γ-H2AX assay. Reports of radiosensitivity after stereotactic radiosurgery (SRS) are uncommon. We describe a case where the clinical, radiological and laboratory findings suggest enhanced radiosensitivity after SRS for an acoustic neuroma. ...[more]

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