Surgical treatment for heart failure: cell-based therapy with engineered tissue.
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ABSTRACT:
SUBMITTER: Lancaster JJ
PROVIDER: S-EPMC7418896 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Surgical treatment for heart failure: cell-based therapy with engineered tissue.
Lancaster Jordan J JJ Koevary Jen Watson JW Chinyere Ikeotunye Royal IR Daugherty Sherry L SL Fox Kenneth A KA Goldman Steven S
Vessel plus 20190917
This review will outline cell-based therapy for heart failure focusing on tissue engineering to deliver cells to the damaged heart. We will present an overview of the central approaches focusing on pluripotent stem cell-derived cells, mechanisms of action, autologous <i>vs</i>. allogeneic cell approaches, immunologic modulation, and safety considerations. We will outline the progress that has been made to-date and define the areas that still need to be investigated in order to advance the field. ...[more]
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